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The Cell Culture Facility at Pushpagiri Research Centre (PRC) is dedicated to in-vitro cell culture research, maintenance of mammalian cell lines, and cell-based experimental studies. The facility maintains cell lines including HepG2, RAW 264.7, L929, and other commonly used cell models. Equipped with essential infrastructure such as CO? incubators, biosafety cabinets, ELISA reader, fluorescence inverted microscope, centrifuges, and other basic laboratory instruments, the facility supports cell maintenance, cytotoxicity assessment, cellular assays, and biomedical research.
Varghese, D. M. G., George V., D. T., Thomas, D. N. G., Pyas, D. A. M., & Maymol Francis, D. A. Marine Based Biomaterials in Dental Regeneration. International Journal of Innovative Research in Medical Science. 2020; 5(10):443 -448.
10.23958/ijirms/vol05-i10/965?Raj, Sheena & Devadathan, A. & James, Baby & Johny, Minimol & George, Emil & Thomas, Nebu & Varghese, Mekha. (2021). Management of complicated crown root fracture using piezo surgery, fiber post and fragment reattachment: A case report. IP Indian Journal of Conservative and Endodontics. 6. 160-165.
10.18231/j.ijce.2021.035Sultan S, Thomas N, Varghese M, Dalvi Y, Joy S, Hall S, Mathew AP. The Design of 3D-Printed Polylactic Acid–Bioglass Composite Scaffold: A Potential Implant Material for Bone Tissue Engineering. Molecules. 2022; 27(21):7214.
10.3390/molecules27217214Thomas NG, Dalvi YB, Fijol N, Shilpa J, Unni R, Binsi PK, et al. Fish scale derived hydroxyapatite incorporated 3D printed PLA scaffold for bone tissue engineering. New Journal of Chemistry. 2024;48(24):10841-51.
Thomas, B., Velliavettil, T.G., Pratheesh, K.V. et al. In vitro and in vivo biocompatibility of a porcine cholecystic extracellular matrix (CECM) membrane for tissue regeneration. BDJ Open 11, 81 (2025).
10.1038/s41405-025-00370-4· Varghese MG, Valliaveettil TG, Puthanpurakkalkizhakkethil Kamalamma B, Varghese N, Dalvi YB, Thomas NG, Anitha Rajeevan R, Chandran A, Anil S. Development and evaluation of a fish skin-derived acellular dermal matrix for diabetic wound healing: In vitro and in vivo assessment. J Biomater Appl. 2026 Jan 30:8853282261422121. doi: 10.1177/08853282261422121.Epub ahead of print. PMID: 41616380.
10.1177/08853282261422121· Varghese MG, Valiaveettil TG, George AK, Rajan S. Ozone in Periodontal Disease Management – A Review. KDJ, August 2019.
Varghese MG, Valiaveettil TG, George AK, Rajan S. Micro RNA’s In Periodontal Disease – A Review. Ann Dent UM. 2020; 27:11-21,.Vol27, No3
10.22452/AdumGrace Varghese M, Thomas A, S R, KM S, Joseph D, Mathew T A, et al. Fabrication Techniques for Scaffolds Applied in Regenerative Medicine [Internet]. Biomedical Engineering. IntechOpen; 2024.
10.5772/intechopen.110827?George Thomas N, Varghese N, Kalarikkal N, Thomas S, Sreedharan M, Sara George S, et al. Toxicity Evaluation and Biocompatibility of Nanostructured Biomaterials [Internet]. Cytotoxicity - Understanding Cellular Damage and Response. IntechOpen; 2023.
10.5772/intechopen.109078?Nebu George Thomas, Mekha Grace Varghese, Prabha Kadakampallil John, Sheena S. Raj, Riya Sara Jacob, Arimboor Maymol Francis, Chapter 10 - Application of nanocomposites in dentistry, Editor(s): Raji Vijayamma, Nandakumar Kalarikkal, Sabu Thomas, In Nanotechnology in Biomedicine, Nanostructured Materials for Biomedical Applications, Elsevier, 2024, Pages 313-337, ISBN 9780323908382
10.1016/B978-0-323-90838-2.00005-9?